![]() Vaccine causes serious but treatable complications in a child, such as an allergic reaction (hives or a rash develops within minutes of the injection). Ask your doctor what you can do for your child to minimize or relieve these effects.Ĭomplications are very rare. Some children may experience a mild fever, fussiness, drowsiness or tenderness at the injection site after a The diphtheria vaccine is effective at preventing diphtheria. Vaccination consists of a series of five shots, typically administered in the arm or thigh, given to children at these ages: The diphtheria, tetanus and pertussis vaccine is one of the childhood vaccinations that doctors in the United States recommend during infancy. The latest version of this vaccine is known as the DTaP vaccine for children and the Tdap vaccine for adolescents and adults. The three-in-one vaccine is known as the diphtheria, tetanus and pertussis vaccine. ![]() The diphtheria vaccine is usually combined with vaccines for tetanus and whooping cough (pertussis). Today, the disease is not only treatable but also preventable with a vaccine. Rates of death are higher in children under age 5 or adults older than age 40.īefore antibiotics were available, diphtheria was a common illness in young children. Diphtheria is fatal about 5% to 10% of the time. With treatment, most people with diphtheria survive these complications, but recovery is often slow. At that point, you might need mechanical assistance to breathe. If the diphtheria toxin damages the nerves that help control muscles used in breathing, these muscles may become paralyzed. Nerves to the arms and legs also may become inflamed, causing muscle weakness. Typical targets are nerves to the throat, where poor nerve conduction may cause difficulty swallowing. At its worst, myocarditis can lead to heart failure and sudden death. Heart damage from myocarditis may be slight or severe. For example, it can damage the heart muscle, causing such complications as inflammation of the heart muscle (myocarditis). The diphtheria toxin may spread through the bloodstream and damage other tissues in the body. At that site, the infection produces a tough, gray membrane made up of dead cells, bacteria and other substances. This toxin damages tissue in the immediate area of infection - usually, the nose and throat. ![]() Diphtheria-causing bacteria may produce a toxin. There were significantly greater number of localized pain and subcutaneous nodules with greater numbers of doses (P less than 0.01). The results obtained in relation to age and the number of doses were: there was a significant increase of localized pain as ages increased (P less than 0.01). No significant differences were found in the appearance of the side-effects between the both, except for localized pain (P less than 0.01) with the national vaccine. Two types of DTP vaccines, one from the Connaught (Canadian) Laboratory and another from the National Institute of Hygiene (Venezuelan) were used. None of the children had convulsions, hypotonic episodes or immediate neurological damage. With respect to local disturbances: pain, 41.6% reddening, 28.0% and subcutaneous nodules, 20.1%. Eighty-seven percent of the children immunized showed the following side-effects in percentages of frequency: fever, 66.0% malaise, 37.8% loss of appetite, 25.0% sleep disorders, 20.4% vomiting, 7.9% and continuous crying, 7.6%. Over 13% of the children were free from side-effects. Side-effects, 48 hours after the vaccination were determined in 730 children between the ages of two months and five years and 11 months. Both the systemic and local reactions caused by the immunization with the vaccine against diphtheria, tetanus and whooping cough were studied. ![]()
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